Morton could not stop its slide against a state-ranked boys basketball opponent.
Manual was ahead 27-11 at halftime en route to a 49-38 non-conference win over the Potters Feb. 12 in Peoria.
Isaac Stephens tallied 11 points to lead Morton, which outscored the Rams 9-2 in the third quarter.
Jared Liddle added nine points for the Potters.
Manual was ranked ninth in the Feb. 6 Associated Press Class 3A state poll before moving up a slot in the updated rankings.
The Rams, who defeated Morton in the Canton Regional final last March, avenged a four-point regular-season loss a year ago at Morton.
Darryl Howell's 18 points topped Manual.
Metamora 45, MHS 42
The Redbirds needed everything they had to stave off the Potters Friday.
Metamora outscored Morton 28-21 in the second half to pull out a 45-42 Mid-Illini Conference home win.
Brent Waibel led the Potters with 13 points, which included 7-of-8 free throws, and seven rebounds.
Corey Dullard added nine points and four boards for the guests, who lost for the second time to Metamora.
The 22-win Redbirds were led by Tianen Chen's 16 points.
Morton led 21-18 at halftime after earning slight advantages in each quarter.
MHS 58, Canton 31
Morton's 12-game overall losing skid is history.
The Potters trounced the Little Giants Saturday, backing up a good performance with an even better one.
Morton (4-22, 2-11) also climbed past East Peoria into seventh place in the M-I after winning its first conference game since Dec. 1 at Dunlap.
The Potters led 14-3 after one period and 27-10 at the break against a Canton squad that fell to 2-4 in the second round of league play.
Dullard had game-high totals of 14 points and seven rebounds at the Potterdome.
Nick Taylor contributed nine points, with 4-of-4 free-throw shooting, and three assists.
Waibel and Jared Liddle had six points apiece. Waibel led Morton with nine boards. Both players made four steals.
Breck Swinford provided five assists and four rebounds. Jake Starkey tallied five points.
Ten of the 12 Potters who participated scored to help the team salvage a season split.
Mason Goforth, with 10 points, was the lone Little Giant to reach double digits. Canton shot just .194 from the floor.
Postseason: Morton plays East Peoria (2-21) at 7:30 p.m. Monday in the quarterfinals of the Class 3A East Peoria Regional.
It will be the second meeting between the rivals in three days.
The winner advances to play No. 1 seed and third-ranked Washington (26-1) at 6 p.m. Tuesday in the semifinals.